Trials Available at Mercyhealth Cancer Care

Breast

NRG BR003– A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without  Carboplatin for Node-Positive or High-Risk Node Negative Triple-Negative Invasive Breast Cancer

SWOG S1207  Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/NEU Negative Breast Cancer

Alliance A011106 – ALTernate approaches for clinical stage II or III Estrogen Receptor positive breast cancer NeoAdjuvant TrEatment (ALTERNATE) in postmenopausal women: A Phase III Study

Alliance A011401 – Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obses Women with Early Breast Cancer

Alliance A011502: A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial

Alliance A211601: Evaluation of Mammographic Breast Density Effect of Aspirin: A Companion to Alliance Study A011502

SWOG S1703: Randomized Non-Inferiority Trial Comparing Overall Survival of Patients Monitored with Serum Rumor Marker Directed Disease Monitoring (STMDDM) Versus Usual Care in Patients with Metastatic Hormone Receptor Positive Breast Cancer

 

Brain/Central Nervous System

No trials currently available.

 

Colon and Rectum

NRG GI004 – Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer

SWOG S1613 – Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

 

Leukemia

No trials currently available.

 

Lung

SWOG S1400 – A Biomarker-Driven Master Protocol For Previously Treated Squamous Cell Lung Cancer

EA5161: Randomized Phase II Clinical Trial of Cisplatin/Carboplatin and Etoposide (CE) Alone or in Combination with Nivolumab as Frontline Therapy for Extensive Stage Small Cell Lung Cancer (ED-SCLC)

 

Mercyhealth Quality of Life Trial

SyMpTOM – Symptom Management Through Oncology Massage

 

Multiple Myeloma

ECOG E1A11  Randomized Phase III Trial of Bortezomib, LENalidomide and Dexamethasone (VRd) Versus Carfilzomib, Lenalidomide and Dexamethasone (CRd) Followed by Limited or Indefinite DURation Lenalidomide MaintenANCE in Patients with Newly Diagnosed Symptomatic Multiple Myeloma (ENDURANCE)

Lynx – A Pilot Study to Evaluate the Therapeutic Response of Tumor Cells Co-Cultured with Non-tumor Cells from Patients with Multiple Myeloma ex vivo.

 

Myelodysplastic Syndrome

No trials currently available.

 

Ovarian

No trials currently available.

 

Prostate

No trials currently available.

 

Thyroid

Alliance A091302 – A Randomised Phase II Study of Sorafenib with or without Everolimus in Patients with Radioactive Iodine Refractory Hürthle Cell Thyroid Cancer

 

Multiple Cancer Sites

EAY131 – Molecular Analysis for Therapy Choice (MATCH)

UW15068 – UWCCC Precision Medicine Molecular Tumor Board

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