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Risk Factors for Premature Menopause

A risk factor is something that increases your likelihood of getting a disease or condition.
Menopause is a natural process, which usually occurs around the age of 50. However, if the normal menstrual cycle is interrupted prior to age 40, it is thought to be abnormal and is referred to as premature menopause. Early menopause is considered as age 40-45 years old.
Risk factors for premature menopause include:
  • Family history of premature menopause
  • Surgical removal of the ovaries— oophorectomy
  • Radiation therapy
  • Chemotherapy
  • Medications that reduce estrogen levels
  • Smoking
  • Autoimmune diseases
  • Medical treatments (pelvic surgery, chemotherapy, or pelvic radiation therapy)

References

Menopause. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114698/Menopause . Updated March 15, 2018. Accessed April 17, 2018.
The menopause years. The American College of Obstetricians and Gynecologists website. Available at: https://www.acog.org/~/media/For%20Patients/faq047.pdf?dmc=1&ts=20130416T1306377302. Updated May 2015. Accessed April 17, 2018.
What is menopause? National Institute on Aging website. Available at: https://www.nia.nih.gov/health/what-menopause. Updated April 17, 2013. Accessed February 27, 2014.

Revision Information

  • Reviewer: EBSCO Medical Review Board Marcie L. Sidman, MD
  • Review Date: 03/2018
  • Update Date: 03/15/2015
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