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Diindolylmethane

Introduction

Diindolylmethane is a compound found in cruciferous vegetables. These vegetables include broccoli, cabbage, kale, and brussels sprouts. The compound has been used to lower markers of cancer. It can be taken as a pill or by eating cruciferous vegetables.

Dosages

150 milligrams twice daily

What Research Shows

Not Enough Data to Assess

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take diindolylmethane for a short time. Not enough studies have been done to say whether it is safe to take for a long period.
Interactions
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.

References

1
Del Priore G, Gudipudi DK, et al. Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecol Oncol. 2010 Mar;116(3):464-467.
2
Castañon A, Tristram A, et al. Effect of diindolylmethane supplementation on low-grade cervical cytological abnormalities: double-blind, randomised, controlled trial. Br J Cancer. 2012 Jan 3;106(1):45-52.

Revision Information

  • Reviewer: EBSCO NAT Review Board Eric Hurwitz, DC
  • Review Date: 02/2020
  • Update Date: 05/27/2020